Programmable 3D Printed Dressing Improves Burn and Cancer Treatments

Programmable 3D Printed Dressing Improves Burn and Cancer Treatments

Customise hydrogel masks. Credit score: College of Waterloo

Scientists have developed a wise wound dressing that makes use of superior polymers for customized remedy of burn victims. The dressing, customizable through 3D printing, adheres nicely to pores and skin and presents time-release remedy for prolonged aid. Potential makes use of additionally embrace fixed drug launch in most cancers remedy and customised beauty functions.

One of many challenges in treating burn victims is the frequency of dressing modifications, which may be extraordinarily painful.

To deliver aid to this and different issues, College of Waterloo researchers have created a brand new kind of wound dressing materials utilizing superior polymers. This new dressing might improve the therapeutic course of for burn sufferers and have potential functions for drug supply in most cancers remedy in addition to within the beauty business.

“To deal with burn victims, we will customise the form utilizing a 3D printer, secondly, the fabric has fine-tuned floor adhesion, which is a key characteristic”, mentioned Dr. Boxin Zhao, a professor in Waterloo’s Division of Chemical Engineering, whose workforce has made important strides in growing clever hydrogel supplies to be used as a reusable wound dressing. “The fabric can simply adhere to the pores and skin and be taken off. It’s a really delicate steadiness inside the materials to make the adhesion work.”

In growing the dressing, the researchers performed a 3D scan of the affected person’s face and physique components to customise it to a person’s wants. This allows the dressing to make good contact with surfaces like noses and fingers, making it superb for creating customized wound dressings for burn sufferers.

The fabric additionally has functions for most cancers remedy. In conventional chemotherapy remedy, a affected person could have to be in a clinic for hours, which may be tiring and uncomfortable. This dressing can present a relentless drug launch exterior the clinic setting, assuaging a number of the challenges related to conventional strategies.

The fabric used to create these sensible dressings features a biopolymer derived from seaweed, a thermally responsive polymer, and cellulose nanocrystals. The dressing’s thermal responsiveness permits it to heat on the pores and skin and gently decrease to room temperature. Moreover, when chilled within the fridge, the dressing expands however shrinks to a smaller dimension at physique temperature, making it simpler and fewer painful to take away. Additionally, the dressing is designed to offer time-release remedy, permitting for longer-lasting ache aid.

“We additionally envision functions within the magnificence and beauty business,” mentioned Zhao, Waterloo’s Endowed Chair in Nanotechnology. “Cosmetologists can make the most of 3D scanning expertise to investigate their purchasers’ facial options and customise hydrogel masks infused with particular facial and pores and skin routine merchandise. Moreover, this revolutionary method can profit plastic surgeons.”

This analysis is proof of idea for Zhao’s Floor Science and Bio- nanomaterials Laboratory Group. The subsequent step for Zhao’s analysis group is to proceed bettering the fabric’s properties to make it more healthy and commercially viable.

A examine highlighting the workforce’s progress was just lately revealed within the Journal of Colloids and Interface Science.

Reference: “Multi-thermo responsive double community composite hydrogel for 3D printing medical hydrogel masks” by Lukas Bauman and Boxin Zhao, 6 February 2023, Journal of Colloids and Interface Science.
DOI: 10.1016/j.jcis.2023.02.021

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